Oral Microbiome Influences Obesity Risk

Published on January 26, 2026 | Translated from Spanish
Conceptual illustration of oral bacteria in the form of colored spheres and rods, interacting with fat molecules and nutrients on a background simulating the inside of the mouth.

The oral microbiome influences obesity risk

A new study indicates that the trillions of bacteria living in our oral cavity, known as the oral microbiome, could be a key factor in determining whether a person develops obesity. 🦠

Bacterial diversity makes the difference

Scientists from the University of Iowa examined saliva samples and found a clear correlation: individuals with a higher body mass index exhibited a significantly less diverse bacterial population in the mouth. This altered microbial composition appears to modify the way the body processes food and accumulates lipids.

Proposed mechanisms of action:
  • Some oral bacteria can trigger inflammatory responses that affect metabolism throughout the body.
  • Certain microorganisms produce compounds that, when ingested, interact with the digestive tract and alter nutrient absorption.
  • This establishes a direct link between oral health and the body's ability to regulate weight, regardless of diet or exercise.
The mouth could be the metabolic gateway that explains part of the obesity epidemic.

Perspectives for future interventions

These discoveries pave the way for investigating interventions aimed at modifying the oral bacterial flora to help control weight. Researchers suggest that specific tools could be developed.

Possible future applications:
  • Oral probiotics formulated to repopulate the mouth with beneficial bacterial strains.
  • Designed mouthwashes that promote the growth of a balanced microbial community.
  • The ultimate goal is to restore a balance that promotes more efficient metabolism and helps prevent weight gain.

Oral care with a new perspective

The results suggest that, beyond regular brushing, caring for our oral bacteria could be relevant for maintaining a healthy weight. This adds a layer of meaning to the well-known phrase "weigh every word", directly linking what happens in our mouth to what the scale reflects. ⚖️