The public health system of England will incorporate a new treatment for vitiligo. It is the cream Opzelura, whose active ingredient is ruxolitinib. This drug represents a different approach by acting on the immunological cause of the disease. It is indicated for those over 12 years old with non-segmental vitiligo when other topical treatments have not worked.
A JAK inhibitor that stops the autoimmune attack on melanocytes 🧬
Opzelura works as a topical inhibitor of the JAK1 and JAK2 enzymes. These enzymes are involved in the signaling that causes the immune system to attack and destroy melanocytes, the cells responsible for skin pigmentation. By blocking this pathway, the autoimmune process is stopped, allowing existing melanocytes to recover and produce pigment again. Trials showed repigmentation in different skin tones.
Checkered skin now has a plan to return to unified color ðŸ¤
It seems that the cowboy style on the skin, with those characteristic white spots, could be numbered for those who suffer from it. After years of treatments that often limited themselves to camouflaging the problem, now a cream arrives that tells our defenses directly: hey, calm down, those cells are ours. That said, the NHS recommends it only if everything else fails, because even for such an advance, you have to go through the proper protocol.