The Fraunhofer IAP and NMI have created a tissue substitute that replicates the mechanical behavior of natural pericardium. The material, developed in the PolyKARD project, flexes under light loads and stiffens under pressure. Its three-layer structure includes an acrylate polyurethane base, a 3D-printed wavy metastructure, and electrospun collagen.
Wavy metastructure controls stiffness 🧬
The technical key lies in the 3D-printed wavy metastructure. This geometry allows the material to deform easily under low stress, but upon reaching a threshold, the waves compress and the material abruptly becomes rigid. The electrospun collagen layer facilitates cell adhesion, while the acrylate polyurethane base provides strength. The design is optimized for industrial transfer.
Your replacement pericardium, now in three layers 🫀
Finally, if your pericardium fails, you can order a new 3D-printed one with 24-hour shipping. Of course, you'll first have to explain to your health insurance that the part includes a layer of electrospun collagen, which sounds like a gourmet pizza ingredient. But rest assured, the wavy metastructure ensures it won't soften even in the most tense moments. Literally.